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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4c3de093a394e683dc64505e04aeff1bdd24308f05539e888fdeee5a82cec48' 
  AND token = 'MP0+SGysL6FonLO2/w8qob4RugVGfrsCt4rOEMo3umE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}