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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb30c9b218aa157674932c7413698c35c99ef30960c018e9d5a37047ee55022a' 
  AND token = 'ZU1LPX6x7SOPHhu8Qha+3YwsgrDUy+ua/mz/yMixDSc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}