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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21664c9dffc4c87918216b440bae551d7694922195e6657794fbd7fd0b50b531' 
  AND token = 'UTV7xh4cD9pDi2m7LbjnHVYRcJ90cezuMHCKYpYGnww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}