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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4eace86f858d19ec95f885245442be00b708521f86d6e054728351a5fbfd8aee' 
  AND token = 'bLZheAcJxpGs2auRcrdnMC4q8WUzpkiKziTNX849y9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}