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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3c38ecf19afb7c481a45ddfc91df6c7d70aae5fc1c212783269adf641b46f17' 
  AND token = '+HugMioCrhfQN6ubryw6kt3Bsjeh4DUGRqZ1q3ih2ic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}