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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb486597972a18c4e4c1c933e539440301a3326b13c3346dfbd8a3c08fc80e0b' 
  AND token = 'bKJG4jGHHecmuM+1nciw3lHgw+KIDx8Nm70W+HEvkWM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}