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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0bb0a4ae4154c8728847392591b222675b0591fc594c5700b12dd15baf29f87e' 
  AND token = 'mPEvun+y4a7Jib1Z/h42SEMTOL65Gd+WmWbcZA+xsH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}