SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf3742f8d4d5153c597edbc0b95bae5c0da82277b79e6e006cd428838c10522a' 
  AND token = 'ioulQe0IvPFgbFOIsNUh4esiy8y4+DwSbxfDHc900Vo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}