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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3651240e8af8e355680a5c31ca07d54de797b92142974f3047a7c7cc819b50a8' 
  AND token = 'x6mbuZaDFmaC0CIPSkn5LRdLgYlSKKO9iBIkh0PJPG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}