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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c406a5c4345be3ea288b90f488368afd80780e5f16b15a5efdc9ef54902be83b' 
  AND token = '9V2wUONVCmC0+kD4tW7ZCH4HN9h3mgjgHPgAW2aye0o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}