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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5d1100af0f4907fbd135c380fc2a262269683f7a44cb6850473b8bd6df078a0' 
  AND token = 'SfCHoJQaktLzamcUAzzRYlonpIC9JQfLWY4icJYpXec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}