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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0fb5d179c5c2e3e7ea5502f570aeb451612d1b24b5782e9032343384eee255a' 
  AND token = 'JHD2XF6p4hH7MHjnVHqlwzSeZfEtBJIl4fk1N/ZOXVc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}