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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1021709662ae4e88cb3b1f354cc6a74679662c19b8fe3ec9af6146ace6959cb6' 
  AND token = 'c8ihvp0uSNcHsSQaKLtQ2lMQxFjeJmRu81IjSUZ2y7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}