SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e04c02aaa47a5bd115bcd896907800d414fb3498ed6c6cd07fba6146250d976a' 
  AND token = '3KuQA07FSBvK1rfp4jP4mKWZ9cKXYQ/mAZWEu4xPWEU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}