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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e74d36feb73641d0c497c03768ed0e8b27e639674e26787c47bb2f777824b93e' 
  AND token = '1cGvJ5rBemQfIbgKmnC8xWLdjMOBd00ShSPgzdgnlnY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}