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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e347533d33ea12725db874ecf7d6e0eb0fa7f193dcd8f63b3473bf20d5953184' 
  AND token = '7XDwzRG+ow4nmbkgbJ6WgN+6zoxu+/gt/s77Vk0i9tg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}