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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a9c53e28e18072f134b2865a4b950f860b79e4e9947a2cf20a00ad4e5059da8' 
  AND token = 'nI231B8accy0qwJDaaG3UlpKMfIlKGUjJhvDflabwKA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}