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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e64bcb81f5b83bbf04a756e5b1db0ef3abdb1c1201b81631db3926712656579f' 
  AND token = '+OB7ncj/22oHMLEcwF7cB9kFAjQGJoHDbPwm56cZ/sc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}