SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '780adc5ee65ff783ffec303a8375083769e5171666b892d2636c2cbb1af956f4' 
  AND token = 'q7lIBueqjuUcUlHoUWOus9hHrQA9Ogov0UJexvORSdw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}