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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8424bf427888d6bf0f0a36af96042bed38929b443194d0eb6f9bb6d6f46f7b00' 
  AND token = 'ZK823YsvDhCTMHsI4DBzkrXFfDWSYOG0IyKA/Mqbw50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}