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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '393e2d171ab8e225fb890c86b18baeda5d3f97f691db4246cc1de7bab393a523' 
  AND token = 'U++OIvpVGdw/PJXUBeCgrdLBLg6NcTn0dTOUM79B4y0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}