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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7abd8632d1adb6d49edfee945fffc9221b919f042878330f0ea0d990933316f' 
  AND token = 'cS1nTuTQbqgHZJK+ojvDLpT4dND/MMe0q7t3lIi7iT4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}