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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '92ce31dc197f5f4d9430feae6cf291fcbb25250ad7b8945bc418d20829e0aeb2' 
  AND token = '1NUmOeKdIiuVbTXF+qpbYMAv6fYENL7zcLduIEiBkmI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}