Sandbox

SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8fab2a89bf2fb6f48925dd1683e954dcbd089542ca3fecd0b11a1d65ec11ea1' 
  AND token = '6ucUkNOIjBLMdUFVEqNSNYs0SgpQ01bh9vrRvVEiQ/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}