SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f647b9509cad4dd82960d15cc34598cefc26789718bb736cd7a03512d51cf011' 
  AND token = 'aMCB0Za9aA/a64Y7ppMy3HE452oIg2k8KYEYD8Kl44M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}