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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2908f428350558180b777a02597432d08a439d50a0f4ebee9d80f205bf6d48ab' 
  AND token = '/fJO6HrSNN1gvN9o4TEfXQPP0n8nTu8gv8vXV9KbkN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}