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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '591399b6e600fa1785089596f34567003d8f5cf9b3531796a6466d7707f378d1' 
  AND token = 'E23TeTf/j4C7FBrTHztQ94L63LSKKv/bJg5DeFyOS5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}