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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b2420593d75f4ac312f137ec9574da4369f811a0134423f359ae438a8ac5bee' 
  AND token = 'W8RuemgjRwOF61FdDVTh/Lrc7HyFIaT9tMEK9Dbjt+I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}