SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c611e134b0446831d0c1fd88d18ee4c37a18611a79399f7b745bc2811c3ec504' 
  AND token = '4l//cEtZwwDgBa34qj0FXTsfD/OSKg1r9MCjawLfjWM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}