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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fc9c132f2d5b33ad56f7d21bc373d19db5d02f44625e8ccab3656b6b6d3ca44' 
  AND token = 'VrOfwdIbCSE04AkH8Hvmwz982BMLVElAr+t/NHrTPAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}