SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2116a19c818cdf09863b7de16366d190c5e2b04cc15728a23c8eae1c8e89dca8' 
  AND token = 'K9hLzJCHuttKfPiGm+1ZzlLtdOLPXsWanhZrGbHeX+U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}