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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '050e04223dada4033c808d7d86c1d80ac0196676dff3782ea656026d14c5f52c' 
  AND token = 'Q7kNg1kXJdXmESZxoS0Fd574Wk+OmkSe+oavH9QMKYk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}