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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42a1d303c48efbf7a5c811cc6f2ab1f474a78944280014729e3ec69c278051da' 
  AND token = 'FhXn/urWIVGN4J1VXR+01HAJARFqTUUic0HrNieg5zM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}