SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f6f2ac2c24ef1e2be85b9a89b5ca62b88be2d66837fed295cbde3edd54315f5' 
  AND token = 'VRy+8YADTvwQKlQ4ncUWfyZ65BdKmusQo2MvjmpqTsA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}