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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2793cc5c8c0deba5d04a09776b5e7a6fe4d350878f49c4e58f242751ce9959ae' 
  AND token = 'DVCJKygUFjfIlI1OMkvp5yGPkdUBGYSIAxJ3vjUdyQo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}