SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fb2ea82704b7143ee365f223f34bb67f85e49e078003d389548746ab82f6d5d' 
  AND token = 'MjKBfzpvI/3/o9mPzE1Eo273ZMtxKu2ilv92KM2UuKs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}