SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c45915ad030629b2ad39024d6257aaa27f44b0a63efb1f66cec22aca24ff69b' 
  AND token = '3hvfRAqw06z0KoWQkA+ILDaZGgWq0d9LA9aI7PpeNyg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}