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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41e5517af5422c1d8f9724ee223b96724933f95a6a2da5f6b0aa274a96d72339' 
  AND token = 'WsQ+0mIC7R/MlGRV/0yJhOXJAUEWQfb4ke8TMHJdgx0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}