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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecbc7a89a57668a878046460719cbfc8c4c4ecedfc6d41bff98be3a6c7c831cd' 
  AND token = 'pkvl8XQKnMUdE/JK3GqygJZ7o9MhJpv+KmF24c2CdPc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}