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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c46ae3cf5cbaccbbd4fe4d683679c529d9d083ba11ac1bd487a2e125969afeb7' 
  AND token = 'xfvcqX7msGRMAQaou1hObJXnM9XXKoluOYid/1c8MzI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}