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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2adb1dd7de02a0e9eaefc685f4487bce1f02c38b3cbb25da708c187f48bfc5c' 
  AND token = 'TbhHLMYuCwsIA4oyRixdm7hUFQv/1p44bPJUI50ttBw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}