SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0465273fd69ce1f5e2dd9954701cf6ac30ea4629d5f548f5144a085a1ee4d92d' 
  AND token = 'DVfEYE4nQw9BeUM+WaNoCtj98/X/KDW+EUnRm3kmyJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}