SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd51a478a395ce28946a1b5f2bd06b7a031c6decaa4fbb2f8429510456b003dc' 
  AND token = '/1k8QUUaM8KV+hc5fKspR5HacYN5UCB7K57BodIpUVk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}