SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40d37bb7ef716c6974d6d2e65ee08daf254938ea3eaa2e27a6d9e325e28190f8' 
  AND token = 'ZoaBec53oMAL4rE/VG3eq+fmxJtuzlLzN1cVqdGkLm8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}