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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81d67ac5e7bcc9d63e719770305f769d14d626c6611d5e6aa82ea7660a3e429f' 
  AND token = 'MYgtePIJ7K/O7iLp01KUXDiCiPijsFih1fhtNpfqBr0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}