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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81c0ab0c1b7ca550b9d4a5ae381f9e998df0c8143cc598dbde674da4d51da074' 
  AND token = 'HkQuMJvzFUugxjrZ6sSIM1bvnzsbxQT8v0lV1mPpCm8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}