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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6ef118e82dc34acc70ee7c4d8165017fc42dc556944f97385dd623b9ced80a5' 
  AND token = 'HLJwEdVLYRWko+x10Cs6y2jyzwS6NxFUK47wEsI0Ozo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}