SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '807b4e6f06cfa25005ac99bfff186ee371169dc414fdde40a0ad1fd3614ea404' 
  AND token = 'BYiD9SfggoP/1iCmuXgDchZt4iFP26Y8Ng56BP56B6M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}