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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ed64e81cebf84b6215e625360fe22be25eaed67cdeed3ce9aa36c603ed0042a' 
  AND token = 'hYG1TaCRZVZnWjT7spMyo+LcqWGtASDXkzc28d+cizk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}