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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65f15619b83f37aed62ff57bf3e6a960fbbd85d4f2ea7c2e9d695cc99041846e' 
  AND token = 'DXVWaSd98qwKQmS1trTlKpQe0ZCOWSHESzMkeUE06Zg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}